WebA synthetic phospho-peptide corresponding to residues surrounding Ser15 of human phospho p53. Formulation: 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA: Isotype: Rabbit IgGk: Preparation: Protein A+G: Recommended Usage: 1µg/mL – 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. WebThe most recent study using analysis of genome-wide binding profiles of phosphorylated p53 has demonstrated that the extent of Ser46 phosphorylation of p53 bound to DNA is higher than Ser15 ...
Critical role for p53-serine 15 phosphorylation in stimulating transactiva…
WebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in … WebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in blocking the proliferative action of damaged cells and act as an anticancer agent. somewhere boy episode 7
Phospho-p53 (Ser315) Polyclonal Antibody - Thermo …
WebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in blocking the proliferative action of damaged cells and act as an anticancer agent. Web80195-1-RR targets Phospho-P53 (Ser15) in WB, FC, ELISA applications and shows reactivity with Human samples. Background Information P53 is a 53 kDa protein that is activated in response to alteration of normal cell homeostasis, including DNA damage, nutrient starvation, heat shock, virus infection, pH change, hypoxia, and oncogene … WebActivation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis . DNA damage induces phosphorylation of p53 at Ser15 and Ser20 and leads to a reduced … somewhere boy how many episodes