Mexiletine pregnancy category
WebbMexiletine (Mexitil) Dose in the treatment of life-threatening ventricular arrhythmias: Oral: Initial: 150 - 200 mg every twice or thrice a day (may load with 400 mg if necessary); adjust the dose as required, dose can be increased 50 or 100 mg every 2 to 3 days up to 300 mg every 8 to 12 hours. Usual dose: 150 - 300 mg every 8 to 12 hours. WebbShort description: Pair of enantiomers . Mexiletine; Clinical data; Trade names: Mexitil, NaMuscla: AHFS/Drugs.com: Monograph: MedlinePlus
Mexiletine pregnancy category
Did you know?
WebbPregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking mexiletine, it may affect your baby. Webb31 okt. 2024 · FDA pregnancy category C. It is not known whether mexiletine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while …
WebbPregnancy. Pregnancy Category (FDA): Pregnancy Category C; Reproduction studies performed with mexiletine in rats, mice and rabbits at doses up to four times the maximum human oral dose (24 mg/kg in a 50 kg patient) revealed no evidence of teratogenicity or impaired fertility but did show an increase in fetal resorption. WebbThe experience with mexiletine in patients with severe renal impairment is limited. Therefore, the use of mexiletine is not recommended in this patient population (see section 4.4). Paediatric population The safety and efficacy of mexiletine in children and adolescents aged 0 to 18 years have not been established. No data are available.
Webb4 nov. 2024 · Brand name: Mexitil Drug class: Class Ib Antiarrhythmics VA class: CV300 Chemical name: 1- (2,6-Dimethylphenoxy)-2-propanamine hydrochloride Molecular … WebbMexilitene, a class 1b antiarrhythmic, was used throughout an entire pregnancy to treat symptomatic premature ventricular contractions in a patient with mitral valve prolapse. Cord blood and maternal serum mexilitene levels at the time of delivery are given. The following conclusions were reached.
Webb7 juli 2024 · Mexitil is a prescription medicine used to treat the symptoms of irregular heartbeats (ventricular tachycardia). Mexitil may be used alone or with other …
WebbOn 19 November 2014, orphan designation (EU/3/14/1353) was granted by the European Commission to Temmler Pharma GmbH & Co. KG, Germany, for mexiletine hydrochloride for the treatment of myotonic disorders. The sponsorship was transferred to Hormosan Pharma GmbH, Germany, in October 2015, to Lupin (Europe) Limited, United Kingdom, … courtyard concerts grand havenWebbAdult: For rapid control of life-threatening cases: 400 mg loading dose, followed by 200 mg 8 hourly. When rapid control of life-threatening cases is not essential: Initially, 200 mg 8 hourly. Doses may be adjusted in increments or decrements of 50 or 100 mg at intervals of at least 2-3 days. Usual dose: 200-300 mg 8 hourly. Max: 400 mg 8 hourly. courtyard columbia northeast/fort jacksonWebbCategories: Pregnancy drugs Category A : These drugs are generally acceptable to use during pregnancy. Controlled research data in animals and humans show no evidence … brian sucheski eye doctor