WebHypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong correlation between elevated levels of HIF-1 and tumor metastasis, angiogenesis, poor patient prognosis as well as tumor resistance therapy. Web23 de jul. de 2024 · HIF1a Antibody (28b) is recommended for detection of HIF-1α of mouse, rat and human origin by WB, IP, IF and IHC (P); also reactive with additional species, …

HIF1A siRNAs

WebThere are several isoforms of the HIF α subunit (2). Studies have found that HIF-1α and HIF-2α expression is increased in some human cancers (2). HIF-1α has both pro- and … lycoming sb475c

SNP rs2057482 in HIF1A gene predicts clinical outcome of

WebMonoclonal Antibody for studying HIF1A. Cited in 31 publications. Validated for WB, IP, IF, F. Available in 2 sizes. Highly specific and rigorously validated in-house, HIF-1α (D5F3M) … Web11 de abr. de 2024 · MB is a common childhood malignancy of the central nervous system, with significant morbidity and mortality. Among the four molecular subgroups, MYC-amplified Group 3 MB is the most aggressive type and has the worst prognosis due to therapy resistance. The present study aimed to investigate the role of activated STAT3 in … Web7 de jun. de 2013 · STUB1 is a critical player in the CMA-dependent degradation of HIF1A. ARPE-19 cells were transfected with STUB1-myc and incubated either in the presence or absence of 200 μM chloroquine, 20 μM MG-132 or 2% O 2 for 8 h or 300 μM CoCl 2 for 6 h. ( A) Immunoprecipitation of myc-tagged STUB1. lycoming sb459