WebMar 1, 2001 · Function. Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to down-regulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by down-regulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. WebJul 7, 2024 · FNDC4, which had been characterized by Bosma et al. [17], is a member of the fibronectin type III domain family (FNDC1-5). FNDC4 is the closest homolog to FNDC5. FNDC4 shares 57% amino acid identity with FNDC5 in …
Correlation of the prognostic value of FNDC4 in glioblastoma with ...
WebOur FNDC4 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the FNDC4 antibody that fits your needs. Choose from 1 of 12 FNDC4 antibodies, which … WebFNDC4 is an ortholog of FNDC5 with 50% identity and 86% similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes. Packaging 10 μg Physical form Lyophilized in PBS. Reconstitution flysafair club member login
FNDC 4 acts as an anti-inflammatory factor to improve colitis
WebJul 1, 2024 · FNDC4 reduced intracytosolic lipid accumulation and stimulated a brown-like pattern in human adipocytes, as evidenced by an upregulated expression of UCP-1 and … WebMar 21, 2024 · FNDC4 (Fibronectin Type III Domain Containing 4) is a Protein Coding gene. Diseases associated with FNDC4 include Colitis and Inflammatory Bowel Disease . An … WebFNDC4 is an anti-inflammatory factor that alters the activation state of macrophages; it is used to treat colitis in mice. However, its role in muscle formation and mechanism of function remains unknown. We found that FNDC4 promotes the bovine MDSCs migration and differentiation. Furthermore, we rep … flysafair.com online check in