Dab2 interacting protein

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August undefined, 2024

WebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a tumor suppressor in cancer progression 7,8. WebNov 18, 2016 · The cytoplasmic Ras-GAP protein DAB2IP (Disabled-2 Interacting Protein) is a negative modulator of multiple oncogenic pathways. DAB2IP is rarely mutated, but frequently downregulated or ...

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WebJun 16, 2003 · Identification of Dvl-3 as a Dab2-interacting protein. (A) Schematic representation of the small-pool cDNA screening strategy using GST–PID.(B) Schematic representation of the domain structure of Dvl … WebMar 21, 2024 · DAB2 (DAB Adaptor Protein 2) is a Protein Coding gene. Diseases associated with DAB2 include Teratocarcinoma and Hypercholesterolemia, Familial, 4 . … ct-5mrn120

Dab2IP regulates neuronal positioning, Rap1 activity and …

WebFeb 15, 2024 · Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for multiple cellular functions. It is involved in many signaling pathways and plays an integral role in vesicular uptake and trafficking, modulating immune function, protein–protein interactions, cellular homeostasis and differentiation, oncogenesis, and inflammatory … WebDOC-2/DAB2 interacting protein (DAB2IP) is a RasGAP protein that shows a suppressive effect on cancer progression. Our previous study showed the involvement of transcription regulation of DAB2IP in metastasis of colorectal cancer (CRC). However, the molecular mechanisms of DAB2IP in regulating the progression of CRC need to be further explored. WebSep 1, 2024 · DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP. mRNA was down-regulated and inversely correlated with miR-1307-3p level in HCC tissues ... earphone is not working in laptop

The role of disabled-2 (Dab2) in diseases - PubMed

The roles of GTPase-activating proteins in regulated cell death …

WebMy project specifically focused on the potential action of a gene fusion ESR1-Dab2, isolated from metastatic breast cancer patients resistant to … http://www.cancerindex.org/geneweb/DAB2.htm earphone jack partsWeb智能制造网会员企业上海谷研实业有限公司提供人蛋白激酶Cα相互作用蛋白α1（PICK1）elisa酶联免疫试剂盒介绍,人蛋白激酶Cα相互作用蛋白α1(PICK1)elisa酶联免疫试剂盒介绍的组成：的安全性：1．避免直接接触终止液和底物A、B。一旦接触到这些液 … earphone jack colour code

"WebApr 1, 2002 · Dab2ip (DOC-2/DAB2 interacting protein) is a RasGAP protein which shows a growth-inhibitory effect in human prostate cancer cell lines. Recent studies have shown … " - Dab2 interacting protein

Dab2 interacting protein

WebMechanistically, DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP mRNA was down-regulated and inversely … WebDescription: Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, mRNA. (from RefSeq NM_032552) RefSeq Summary (NM_032552): DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 …

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WebApr 1, 2012 · This indicates that the interaction between Dab2 and a DPF-interacting protein is essential for Dab2 function when AP2 levels are low. This DPF-interacting protein is likely FCHO2. While this requirement is only revealed under artificial conditions, its discovery adds to the understanding of the complex interactions occurring within a … WebOct 18, 2024 · Some GAPs can promote apoptosis of tumor cells to protect the organism. p120RasGAP, regulator of G-protein signaling 3 (RGS3), deleted in liver cancer 1 (DLC1), DOC-2/DAB2 interacting protein (DAB2IP), and STARD13 are typical examples because the five GAPs can influence the balance of antiapoptotic proteins and proapoptotic …

WebOct 4, 2016 · By interacting with other cellular factors through these motifs, Dab2 elicits its functions in endocytosis, differentiation, and immune response and is involved in the cell signaling pathways of Ras-mitogen activated protein kinase (MAPK), Wnt, TGF-β, c-Src and RhoA-ROCK [24, 27–36]. Web大鼠脂蛋白脂酶(lpl)elisa检测试剂盒，产品常见搜索词：大鼠脂蛋白脂酶(lpl)elisa检测试剂盒价格，大鼠脂蛋白脂酶(lpl)elisa检测试剂盒品牌，公司专业供应elisa试剂盒产品，公司长足发展酶联免疫产品，全力打造elisa试剂盒网络超市，形成国内elisa试剂盒核航母，多国elisa试剂盒特权代理，给客户真 ...

Web丁香通为您提供DAB2RabbitpA商品详情介绍：价格：￥600 - 1800，货号：db9976，品牌：戴格，详见丁香通DAB2RabbitpA商品详情页； WebSep 1, 2024 · Mechanistically, DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP mRNA was down-regulated and …

WebApr 1, 2002 · Human DAB2IP (for DAB2 interaction protein) is a novel member of the RasGTPase-activating protein family. It interacts directly with DAB2, which suppresses growth of many cancer types. We demonstrated that DAB2IP is often downregulated in human prostate cancer cell lines. The predicted DAB2IP protein (967 amino acids) …

WebFeb 3, 2015 · Dab2 is an adapter protein involved in receptor-mediated signaling, endocytosis, cell adhesion, hematopoietic cell differentiation, and angiogenesis. It plays … earphone iphone connectorWebFeb 7, 2024 · Specifically, we find that Dab2 myosin interacting region (MIR) binds myosin VI with a moderate affinity (184 nM) and single … ct-5hatWebThe 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a … ct5mcgagWebSep 1, 2024 · Mechanistically, DAB2 interacting protein (DAB2IP) was screened as a direct target of miR-1307-3p. The expression of DAB2IP mRNA was down-regulated and inversely correlated with miR-1307-3p level in HCC tissues. miR-1307-3p knockdown increased the level of DAB2IP in HCC cells. Luciferase reporter assay confirmed the … earphone extenderWebClinVar archives and aggregates information about relationships among variation and human health. earphone language translatorWebSep 17, 2024 · Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein family, and functions as a … earphone laptop not workingWebThe ELISA kits listed below target Dab2, the symbol for the human gene, DAB adaptor protein 2. The protein encoded by DAB2 has a predicted amino acid length of 770, a mass of 82.4 kDa, and a cytoplasmic subcellular localization. There are currently 3 reported isoforms. DAB2 may also be known by the following names: differentially-expressed ... ct-5mrn-600at